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A theory of multi-task computation and task selection

Neural activity during the performance of a stereotyped behavioral task is often described as low-dimensional, occupying only a limited region in the space of all firing-rate patterns. This region has been referred to as the "neural manifold" …

Associative synaptic plasticity creates dynamic persistent activity

In biological neural circuits, the dynamics of neurons and synapses are tightly coupled. We study the consequences of this coupling and show that it enables a novel form of working memory. In recurrent neural network models with ongoing Hebbian …

Transient dynamics of associative memory models

Associative memory models such as the Hopfield network and its dense generalizations with higher-order interactions exhibit a "blackout catastrophe"--a discontinuous transition where stable memory states abruptly vanish when the number of stored …

Symmetries and continuous attractors in disordered neural circuits

A major challenge in neuroscience is reconciling idealized theoretical models with complex, heterogeneous experimental data. We address this challenge through continuous-attractor networks, which model how neural circuits represent continuous …